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Slide LudwigLab Biocatalysis & Biosensing Research Group

Fermentation Laboratory

For the production of proteins in the 100 mg to 100-g scale bioreactors are used. Starting from multi-reaction vessels with 400-mL volume for parallel process optimization, the range of bioreactors includes 5- and 10-L vessels up to our largest fermenters with 42- and 70-L vessels. Additional equipment is necessary for the cell harvest by centrifugation and homogenization of cells by cell disruption methods. To autoclave the fermenters and sterilize biological material the laboratory features two powerful steam generators and a huge autoclave.

Equipment
Infors HT Multifors Parallel Bioreactor System
2 Eppendorf BioFlo 120 equipped with 5-L and 10-L Benchtop Bioreactors
Applikon Pilot System 70-L Bioreactor
Applikon Pilot System 40-L Bioreactor
2 Trevil 1624 Steam Generators
Sorvall Evolution RC Superspeed Centrifuge
Sorvall RC26 Plus Refrigerated Centrifuge
APV 1000 Laboratory Homogenizer
Aminco French Pressure Cell Press
Thermo Scientific Safe 2020 Class II Biological Safety Cabinet
Thermo Scientific Varioklav Classic Autoclave